The narrator of They Rise is a gritty and resourceful individual who is determined to survive the zombie outbreak. They are fiercely independent and willing to do whatever it takes to stay alive, but they also have a soft spot for those in need and will go out of their way to help others.

The game takes place in Houston, where a mysterious outbreak has caused the dead to rise and attack the living. The narrator is one of the few remaining survivors, and they must navigate the treacherous landscape to find safety and supplies. Along the way, they will encounter other survivors, some of whom will become allies, while others will become enemies.